Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening.
Stem Cell Res
; 60: 102673, 2022 04.
Article
em En
| MEDLINE
| ID: mdl-35074713
ABSTRACT
In this paper, we describe the generation and validation of human induced pluripotent stem cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs) from 6 epilepsy patients using a non-integrative Sendai virus vector. These human cellular models will enable patient-specific drug screening to improve outcomes for individuals with this disorder.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Epilepsia
/
Células-Tronco Pluripotentes Induzidas
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Stem Cell Res
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Austrália