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Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying ß-arrestin transducer bias.
Kawakami, Kouki; Yanagawa, Masataka; Hiratsuka, Suzune; Yoshida, Misaki; Ono, Yuki; Hiroshima, Michio; Ueda, Masahiro; Aoki, Junken; Sako, Yasushi; Inoue, Asuka.
Afiliação
  • Kawakami K; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Yanagawa M; Cellular Informatics Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Hiratsuka S; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Yoshida M; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Ono Y; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Hiroshima M; Cellular Informatics Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Ueda M; Laboratory for Cell Signaling Dynamics, RIKEN BDR, 6-2-3, Furuedai, Suita, Osaka, 565-0874, Japan.
  • Aoki J; Laboratory for Cell Signaling Dynamics, RIKEN BDR, 6-2-3, Furuedai, Suita, Osaka, 565-0874, Japan.
  • Sako Y; Laboratory of Single Molecule Biology, Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Inoue A; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Nat Commun ; 13(1): 487, 2022 01 25.
Article em En | MEDLINE | ID: mdl-35078997
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Angiotensina II / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptor Tipo 1 de Angiotensina / Quinase 2 de Receptor Acoplado a Proteína G / Quinase 5 de Receptor Acoplado a Proteína G / Beta-Arrestinas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Angiotensina II / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptor Tipo 1 de Angiotensina / Quinase 2 de Receptor Acoplado a Proteína G / Quinase 5 de Receptor Acoplado a Proteína G / Beta-Arrestinas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão