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SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances.
Fuentes-Fayos, Antonio C; Pérez-Gómez, Jesús M; G-García, Miguel E; Jiménez-Vacas, Juan M; Blanco-Acevedo, Cristóbal; Sánchez-Sánchez, Rafael; Solivera, Juan; Breunig, Joshua J; Gahete, Manuel D; Castaño, Justo P; Luque, Raúl M.
Afiliação
  • Fuentes-Fayos AC; Maimonides Biomedical Research Institute of Cordoba (IMIBIC), 14004, Córdoba, Spain.
  • Pérez-Gómez JM; Department of Cell Biology, Physiology and Immunology, University of Cordoba, 14004, Cordoba, Spain.
  • G-García ME; Reina Sofia University Hospital (HURS), 14004, Cordoba, Spain.
  • Jiménez-Vacas JM; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), 14004, Cordoba, Spain.
  • Blanco-Acevedo C; Maimonides Biomedical Research Institute of Cordoba (IMIBIC), 14004, Córdoba, Spain.
  • Sánchez-Sánchez R; Department of Cell Biology, Physiology and Immunology, University of Cordoba, 14004, Cordoba, Spain.
  • Solivera J; Reina Sofia University Hospital (HURS), 14004, Cordoba, Spain.
  • Breunig JJ; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), 14004, Cordoba, Spain.
  • Gahete MD; Maimonides Biomedical Research Institute of Cordoba (IMIBIC), 14004, Córdoba, Spain.
  • Castaño JP; Department of Cell Biology, Physiology and Immunology, University of Cordoba, 14004, Cordoba, Spain.
  • Luque RM; Reina Sofia University Hospital (HURS), 14004, Cordoba, Spain.
J Exp Clin Cancer Res ; 41(1): 39, 2022 Jan 27.
Article em En | MEDLINE | ID: mdl-35086552
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Glioblastoma / Proteína bcl-X / Beta Catenina / Serina-Treonina Quinases TOR / Fatores de Processamento de RNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Glioblastoma / Proteína bcl-X / Beta Catenina / Serina-Treonina Quinases TOR / Fatores de Processamento de RNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha