Metformin prevents endothelial oxidative stress and microvascular insulin resistance during obesity development in male rats.

Liu, Jia; Aylor, Kevin W; Chai, Weidong; Barrett, Eugene J; Liu, Zhenqi

Liu, Jia; Aylor, Kevin W; Chai, Weidong; Barrett, Eugene J; Liu, Zhenqi.

Afiliação

Liu J; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Aylor KW; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Chai W; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Barrett EJ; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Liu Z; Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.

Am J Physiol Endocrinol Metab ; 322(3): E293-E306, 2022 03 01.

Article em En | MEDLINE | ID: mdl-35128961

Assuntos

Resistência à Insulina; Metformina; Animais; Glucose/metabolismo; Inflamação/metabolismo; Insulina/metabolismo; Resistência à Insulina/fisiologia; Masculino; Metformina/farmacologia; Músculo Esquelético/metabolismo; Obesidade/metabolismo; Estresse Oxidativo; Ratos

Palavras-chave

endothelial dysfunction; inflammation; metformin; microvasculature; obesity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Metformina Limite: Animals Idioma: En Revista: Am J Physiol Endocrinol Metab Assunto da revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article

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