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Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine.
Muramatsu, Hiromi; Lam, Kieu; Bajusz, Csaba; Laczkó, Dorottya; Karikó, Katalin; Schreiner, Petra; Martin, Alan; Lutwyche, Peter; Heyes, James; Pardi, Norbert.
Afiliação
  • Muramatsu H; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lam K; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada.
  • Bajusz C; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA; Biotechnological National Laboratory, Institute of Genetics, Biological Research Centre, Szeged 6726, Hungary.
  • Laczkó D; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Karikó K; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; BioNTech RNA Pharmaceuticals, Mainz 55131, Germany.
  • Schreiner P; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada.
  • Martin A; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada.
  • Lutwyche P; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada.
  • Heyes J; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada.
  • Pardi N; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: pnorbert@pennmedicine.upenn.edu.
Mol Ther ; 30(5): 1941-1951, 2022 05 04.
Article em En | MEDLINE | ID: mdl-35131437
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Nanopartículas / COVID-19 Limite: Animals Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Nanopartículas / COVID-19 Limite: Animals Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos