Endocarditis Caused by Nontypeable Streptococcus pneumoniae.

Henriet, Stefanie S V; Langereis, Jeroen D; Lo, Stephanie W; Bentley, Stephen; Mesman, Rob J; Fejzic, Zina; van Niftrik, Laura; van Sorge, Nina M; Wertheim, Heiman F L; de Jonge, Marien I; Cremers, Amelieke J H

Henriet, Stefanie S V; Langereis, Jeroen D; Lo, Stephanie W; Bentley, Stephen; Mesman, Rob J; Fejzic, Zina; van Niftrik, Laura; van Sorge, Nina M; Wertheim, Heiman F L; de Jonge, Marien I; Cremers, Amelieke J H.

Afiliação

Henriet SSV; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Langereis JD; Laboratory of Medical Immunology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Lo SW; Parasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Bentley S; Parasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Mesman RJ; Department of Microbiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University, Nijmegen, The Netherlands.
Fejzic Z; Department of Pediatric Cardiology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.
van Niftrik L; Department of Microbiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University, Nijmegen, The Netherlands.
van Sorge NM; Department of Medical Microbiology and Infection Prevention and Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Wertheim HFL; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
de Jonge MI; Laboratory of Medical Immunology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Cremers AJH; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

Clin Infect Dis ; 75(4): 719-722, 2022 09 10.

Article em En | MEDLINE | ID: mdl-35134152

ABSTRACT

ABSTRACT

The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.

Assuntos

Endocardite Bacteriana; Endocardite; Infecções Pneumocócicas; Pneumonia; Endocardite/diagnóstico; Endocardite Bacteriana/diagnóstico; Humanos; Lactente; Infecções Pneumocócicas/diagnóstico; Streptococcus pneumoniae

Palavras-chave

Streptococcus pneumoniae; bacterial polysaccharide capsule; infective endocarditis; pathogenesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Pneumonia / Endocardite / Endocardite Bacteriana Tipo de estudo: Diagnostic_studies Limite: Humans / Infant Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

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