Organ-on-a-chip platforms as novel advancements for studying heterogeneity, metastasis, and drug efficacy in breast cancer.

Kalot, Rita; Mhanna, Rami; Talhouk, Rabih

Kalot, Rita; Mhanna, Rami; Talhouk, Rabih.

Afiliação

Kalot R; Department of Biology, Faculty of Arts and Sciences, American University of Beirut, Beirut, Beirut 1107 2020, Lebanon.
Mhanna R; Department of Biomedical Engineering, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut, Beirut 1107 2020, Lebanon.
Talhouk R; Department of Biology, Faculty of Arts and Sciences, American University of Beirut, Beirut, Beirut 1107 2020, Lebanon. Electronic address: rtalhouk@aub.edu.lb.

Pharmacol Ther ; 237: 108156, 2022 09.

Article em En | MEDLINE | ID: mdl-35150784

Assuntos

Neoplasias da Mama; Biomimética/métodos; Neoplasias da Mama/tratamento farmacológico; Avaliação Pré-Clínica de Medicamentos/métodos; Feminino; Humanos; Dispositivos Lab-On-A-Chip; Microfluídica/métodos

Palavras-chave

Breast cancer; Cell heterogeneity; Cytotoxicity; Drug testing; Extracellular matrix; Metastasis; Microfluidic technology; Organ-on-a-chip; Stroma; Tumor microenvironment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Limite: Female / Humans Idioma: En Revista: Pharmacol Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Líbano

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