Downregulation of VAP-1 in OSCC suppresses tumor growth and metastasis via NF-&#954;B/IL-8 signaling and reduces neutrophil infiltration.

Xu, Qiongdong; Chen, Xueru; Yu, Tao; Tang, Qinchao; Zhou, Zhuoqian; Wang, Hongyu; Huang, Wanqian; Huang, Tianjing; Liang, Feixin

Downregulation of VAP-1 in OSCC suppresses tumor growth and metastasis via NF-κB/IL-8 signaling and reduces neutrophil infiltration.

Xu, Qiongdong; Chen, Xueru; Yu, Tao; Tang, Qinchao; Zhou, Zhuoqian; Wang, Hongyu; Huang, Wanqian; Huang, Tianjing; Liang, Feixin.

Afiliação

Xu Q; Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Nanning, China.
Chen X; Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Nanning, China.
Yu T; Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Nanning, China.
Tang Q; Guangxi Clinical Research Center for Craniofacial Deformity, Nanning, China.
Zhou Z; Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Nanning, China.
Wang H; Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Nanning, China.
Huang W; Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Nanning, China.
Huang T; Guangxi Clinical Research Center for Craniofacial Deformity, Nanning, China.
Liang F; Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Nanning, China.

J Oral Pathol Med ; 51(4): 332-341, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35174543

Assuntos

Carcinoma de Células Escamosas; Neoplasias de Cabeça e Pescoço; Neoplasias Bucais; Animais; Carcinoma de Células Escamosas/patologia; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células/genética; Regulação para Baixo; Neoplasias de Cabeça e Pescoço/genética; Humanos; Inflamação; Interleucina-8/metabolismo; Camundongos; Neoplasias Bucais/patologia; NF-kappa B/metabolismo; Infiltração de Neutrófilos; Carcinoma de Células Escamosas de Cabeça e Pescoço; Microambiente Tumoral

Palavras-chave

IL-8; NF-κB; OSCC microenvironment; VAP-1; neutrophils

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Bucais / Carcinoma de Células Escamosas / Neoplasias de Cabeça e Pescoço Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Oral Pathol Med Assunto da revista: ODONTOLOGIA / PATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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