The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation.

Wu, Wenjing; Takahashi, Yusuke; Shin, Henry Younghwa; Ma, Xiang; Moiseyev, Gennadiy; Ma, Jian-Xing

Wu, Wenjing; Takahashi, Yusuke; Shin, Henry Younghwa; Ma, Xiang; Moiseyev, Gennadiy; Ma, Jian-Xing.

Afiliação

Wu W; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Takahashi Y; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Shin HY; Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Ma X; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Moiseyev G; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Ma JX; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.

Proc Natl Acad Sci U S A ; 119(11): e2115202119, 2022 03 15.

Article em En | MEDLINE | ID: mdl-35271391

Assuntos

Proteínas do Olho; Genes Dominantes; Distrofias Retinianas; cis-trans-Isomerases; Animais; Proteínas do Olho/genética; Camundongos; Camundongos Knockout; Mutação; Retina/enzimologia; Retina/patologia; Distrofias Retinianas/genética; Visão Ocular; cis-trans-Isomerases/genética

Palavras-chave

RPE65; photoreceptor; retinal degeneration; visual cycle

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cis-trans-Isomerases / Proteínas do Olho / Distrofias Retinianas / Genes Dominantes Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google