Convergent Evolution of Antibiotic Tolerance in Patients with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia.

Elgrail, Mitra M; Chen, Edwin; Shaffer, Marla G; Srinivasa, Vatsala; Griffith, Marissa P; Mustapha, Mustapha M; Shields, Ryan K; Van Tyne, Daria; Culyba, Matthew J

Elgrail, Mitra M; Chen, Edwin; Shaffer, Marla G; Srinivasa, Vatsala; Griffith, Marissa P; Mustapha, Mustapha M; Shields, Ryan K; Van Tyne, Daria; Culyba, Matthew J.

Afiliação

Elgrail MM; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Chen E; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Shaffer MG; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Srinivasa V; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Griffith MP; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Mustapha MM; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Shields RK; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Van Tyne D; Department of Medicine, Division of Infectious Diseases, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.
Culyba MJ; Center for Evolutionary Biology and Medicine, University of Pittsburghgrid.21925.3d School of Medicine, Pittsburgh, Pennsylvania, USA.

Infect Immun ; 90(4): e0000122, 2022 04 21.

Article em En | MEDLINE | ID: mdl-35285704

Assuntos

Bacteriemia; Infecção Hospitalar; Staphylococcus aureus Resistente à Meticilina; Infecções Estafilocócicas; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Bacteriemia/microbiologia; Infecção Hospitalar/microbiologia; Humanos; Staphylococcus aureus Resistente à Meticilina/genética; Testes de Sensibilidade Microbiana; Infecções Estafilocócicas/microbiologia

Palavras-chave

MRSA; antibiotic tolerance; stringent response; tricarboxylic acid cycle; within-host evolution

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Infecção Hospitalar / Bacteriemia / Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Infect Immun Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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