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Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.
Nijhuis, Anke; Sikka, Arti; Yogev, Orli; Herendi, Lili; Balcells, Cristina; Ma, Yurui; Poon, Evon; Eckold, Clare; Valbuena, Gabriel N; Xu, Yuewei; Liu, Yusong; da Costa, Barbara Martins; Gruet, Michael; Wickremesinghe, Chiharu; Benito, Adrian; Kramer, Holger; Montoya, Alex; Carling, David; Want, Elizabeth J; Jamin, Yann; Chesler, Louis; Keun, Hector C.
Afiliação
  • Nijhuis A; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Sikka A; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Yogev O; Division of Clinical Studies, The Institute of Cancer Research, London, UK.
  • Herendi L; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Balcells C; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Ma Y; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Poon E; Division of Clinical Studies, The Institute of Cancer Research, London, UK.
  • Eckold C; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Valbuena GN; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Xu Y; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Liu Y; Department of Surgery & Cancer, Imperial College London, London, UK.
  • da Costa BM; Division of Clinical Studies, The Institute of Cancer Research, London, UK.
  • Gruet M; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Wickremesinghe C; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Benito A; Department of Surgery & Cancer, Imperial College London, London, UK.
  • Kramer H; Medical Research Council London Institute of Medical Science, London, UK.
  • Montoya A; Medical Research Council London Institute of Medical Science, London, UK.
  • Carling D; Medical Research Council London Institute of Medical Science, London, UK.
  • Want EJ; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Jamin Y; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London and Royal Marsden NHS Trust, London, UK.
  • Chesler L; Division of Clinical Studies, The Institute of Cancer Research, London, UK.
  • Keun HC; Department of Surgery & Cancer, Imperial College London, London, UK. h.keun@imperial.ac.uk.
Nat Commun ; 13(1): 1380, 2022 03 16.
Article em En | MEDLINE | ID: mdl-35296644

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos e Proteínas de Sinalização Intracelular / Neuroblastoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos e Proteínas de Sinalização Intracelular / Neuroblastoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido