Single-cell transcriptome profile of mouse skin undergoing antigen-driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions.

Leyva-Castillo, Juan Manuel; Sun, Liang; Wu, Shih-Ying; Rockowitz, Shira; Sliz, Piotr; Geha, Raif S

Leyva-Castillo, Juan Manuel; Sun, Liang; Wu, Shih-Ying; Rockowitz, Shira; Sliz, Piotr; Geha, Raif S.

Afiliação

Leyva-Castillo JM; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: Manuel.LeyvaCastillo@childrens.harvard.edu.
Sun L; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Mass.
Wu SY; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Mass.
Rockowitz S; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Mass.
Sliz P; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Mass; Division of Molecular Medicine, Boston Children's Hospital, Boston, Mass.
Geha RS; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: raif.geha@childrens.harvard.edu.

J Allergy Clin Immunol ; 150(2): 373-384, 2022 08.

Article em En | MEDLINE | ID: mdl-35300986

Assuntos

Dermatite Atópica; Animais; Modelos Animais de Doenças; Células Endoteliais/metabolismo; Humanos; Inflamação; Camundongos; Camundongos Endogâmicos BALB C; Ovalbumina; Pele; Células Th2; Transcriptoma

Palavras-chave

Atopic dermatitis; allergic skin inflammation; single-cell RNA-Seq

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dermatite Atópica Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2022 Tipo de documento: Article

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