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Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds.
Guilhon-Simplicio, Fernanda; Serrão, Carlos Klinger Rodrigues; Pinto, Ana Cristina da Silva; Pacheco, Paulo Anastácio Furtado; Faria, Robson Xavier; da Rocha, David Rodrigues; Ferreira, Vitor Francisco; Pereira-Junior, Raimundo Carlos; Matheeussen, An; Baán, Adrienn; Kiekens, Filip; de Meneses Pereira, Maria; Lima, Emerson Silva; Winter, Hans De; Cos, Paul.
Afiliação
  • Guilhon-Simplicio F; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
  • Serrão CKR; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
  • Pinto ACDS; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
  • Pacheco PAF; Department of Chemistry, Fluminense Federal University, Niterói, Brazil.
  • Faria RX; Department of Chemistry, Fluminense Federal University, Niterói, Brazil.
  • da Rocha DR; Department of Chemistry, Fluminense Federal University, Niterói, Brazil.
  • Ferreira VF; Faculty of Pharmacy, Fluminense Federal University, Niterói, Brazil.
  • Pereira-Junior RC; Superior Studies Center, Amazonas State University, Tefé, Brazil.
  • Matheeussen A; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
  • Baán A; Laboratory of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
  • Kiekens F; Laboratory of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
  • de Meneses Pereira M; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
  • Lima ES; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
  • Winter H; Laboratory of Medicinal Chemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
  • Cos P; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Chem Biol Drug Des ; 99(6): 868-883, 2022 06.
Article em En | MEDLINE | ID: mdl-35313075
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Trypanosoma cruzi / Doença de Chagas / Leishmania infantum Limite: Humans Idioma: En Revista: Chem Biol Drug Des Assunto da revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Trypanosoma cruzi / Doença de Chagas / Leishmania infantum Limite: Humans Idioma: En Revista: Chem Biol Drug Des Assunto da revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil