Nuclear protein of the testis midline carcinoma of the thorax.
Jpn J Clin Oncol
; 52(6): 531-538, 2022 May 31.
Article
em En
| MEDLINE
| ID: mdl-35325167
Nuclear protein of the testis (NUT) midline carcinoma (NMC) is a rare tumor that typically presents in the head, neck, and chest region. NMC is characterized by rearrangement of the NUTM1 gene. It mainly affects children and young adults and is rapidly progressive and lethal. Reportedly, the prognoses of NMCs of the head and neck improve following aggressive initial surgical resection +/- postoperative chemoradiotherapy (CRT) or radiotherapy (RT). However, as NMC of the thorax was identified later, treatments to improve its prognosis are yet to be identified. Our review reveals that NMC is an extremely rare cancer, and most patients remain undiagnosed. Furthermore, this review outlines the clinical characteristics of NMC of the thorax and the prospects for its treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Testiculares
/
Carcinoma
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Child
/
Humans
/
Male
Idioma:
En
Revista:
Jpn J Clin Oncol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Japão