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USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
Prieto-Garcia, Cristian; Hartmann, Oliver; Reissland, Michaela; Braun, Fabian; Bozkurt, Süleyman; Pahor, Nikolett; Fuss, Carmina; Schirbel, Andreas; Schülein-Völk, Christina; Buchberger, Alexander; Calzado Canale, Marco A; Rosenfeldt, Mathias; Dikic, Ivan; Münch, Christian; Diefenbacher, Markus E.
Afiliação
  • Prieto-Garcia C; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Hartmann O; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Reissland M; Molecular Signaling Group, Institute of Biochemistry II, Goethe University Frankfurt, Germany.
  • Braun F; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Bozkurt S; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Pahor N; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Fuss C; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Schirbel A; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Schülein-Völk C; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Buchberger A; Protein Quality Control, Institute of Biochemistry II, Goethe University Frankfurt, Germany.
  • Calzado Canale MA; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Rosenfeldt M; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Dikic I; Protein Stability and Cancer Group, Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany.
  • Münch C; Mildred Scheel Early Career Center, Wuerzburg, Germany.
  • Diefenbacher ME; Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Germany.
Mol Oncol ; 16(17): 3082-3106, 2022 09.
Article em En | MEDLINE | ID: mdl-35364627

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas B-raf Limite: Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas B-raf Limite: Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha