Circular RNA circPSAP functions as an efficient miR-331-3p sponge to regulate proliferation, apoptosis and bortezomib sensitivity of human multiple myeloma cells by upregulating HDAC4.

Ma, Hongyan; Shen, Liyun; Yang, Hua; Gong, Hongtao; Du, Xingjun

Ma, Hongyan; Shen, Liyun; Yang, Hua; Gong, Hongtao; Du, Xingjun.

Afiliação

Ma H; Department of Hematology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China. Electronic address: mahongyan201@163.com.
Shen L; Department of Hematology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China.
Yang H; Department of Hematology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China.
Gong H; Department of Hematology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China.
Du X; Department of Hematology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China.

J Pharmacol Sci ; 149(1): 27-36, 2022 May.

Article em En | MEDLINE | ID: mdl-35369902

Assuntos

MicroRNAs; Mieloma Múltiplo; Apoptose/genética; Bortezomib/farmacologia; Proliferação de Células/genética; Histona Desacetilases/genética; Humanos; MicroRNAs/genética; MicroRNAs/metabolismo; Mieloma Múltiplo/tratamento farmacológico; Mieloma Múltiplo/genética; RNA Circular/genética; Proteínas Repressoras/genética

Palavras-chave

CircPSAP; HDAC4; Multiple myeloma (MM); Sponge; miR-331-3p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Mieloma Múltiplo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Pharmacol Sci Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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