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Ancestry adjustment improves genome-wide estimates of regional intolerance.
Hayeck, Tristan J; Stong, Nicholas; Baugh, Evan; Dhindsa, Ryan; Turner, Tychele N; Malakar, Ayan; Mosbruger, Timothy L; Shaw, Grace Tzun-Wen; Duan, Yuncheng; Ionita-Laza, Iuliana; Goldstein, David; Allen, Andrew S.
Afiliação
  • Hayeck TJ; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Stong N; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Baugh E; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Dhindsa R; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Turner TN; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Malakar A; Department of Genetics, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Mosbruger TL; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Shaw GT; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Duan Y; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Ionita-Laza I; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27710, USA.
  • Goldstein D; Department of Biostatistics Columbia University, New York, NY 10032, USA.
  • Allen AS; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY 10032, USA.
Genetics ; 221(2)2022 05 31.
Article em En | MEDLINE | ID: mdl-35385101
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Genômica Limite: Humans Idioma: En Revista: Genetics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Genômica Limite: Humans Idioma: En Revista: Genetics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos