Keratoconjunctivitis as a Single Entity in X-linked Agammaglobulinemia?
Ocul Immunol Inflamm
; 31(3): 665-670, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-35404736
ABSTRACT
PURPOSE:
To report a case of a male patient with a severe corneal and conjunctival immunopathy likely caused by an X-linked agammaglobulinemia.METHODS:
A clinical case report with observation results from 2001-2021.RESULTS:
A severe corneal immunopathy of both eyes is reported in a retrospective long-term observation of nearly twenty years in a 32-year-old male patient with X-linked agammaglobulinemia (XLA). A chronic progressive corneal scarring with a loss of visual acuity and typical symptoms of a phlyctenular keratoconjunctivitis were observed.CONCLUSION:
Whereas steroid eye drops like dexamethasone could control the symptoms and the corneal scarring progression as short time therapy options, ciclosporin A eye drops showed problems in therapy adherence in long-time use. Antibiotic eye drops supported the anti-inflammatory therapy effects, but no typical pathogen was detected. Antineovascular subconjunctival application did not show any relevant effect in one-time use. Artificial tears were needed as basic therapy.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cicatriz
/
Ceratoconjuntivite
Limite:
Humans
/
Male
Idioma:
En
Revista:
Ocul Immunol Inflamm
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Alemanha