Blockade of TGF-ß (Transforming Growth Factor Beta) Signaling by Deletion of <i>Tgfbr2</i> in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report.

Lee, Chloe Y; Angelov, Stoyan N; Zhu, Jay; Bi, Lianxiang; Sanford, Nicole; Alp Yildirim, Ilkay; Dichek, David A

Blockade of TGF-ß (Transforming Growth Factor Beta) Signaling by Deletion of Tgfbr2 in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report.

Lee, Chloe Y; Angelov, Stoyan N; Zhu, Jay; Bi, Lianxiang; Sanford, Nicole; Alp Yildirim, Ilkay; Dichek, David A.

Afiliação

Lee CY; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.
Angelov SN; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.
Zhu J; Department of Surgery (J.Z.), University of Washington School of Medicine, Seattle.
Bi L; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.
Sanford N; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.
Alp Yildirim I; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.
Dichek DA; Department of Medicine (C.Y.L., S.N.A., L.B., N.S., I.A.Y., D.A.D.), University of Washington School of Medicine, Seattle.

Arterioscler Thromb Vasc Biol ; 42(6): 764-771, 2022 06.

Article em En | MEDLINE | ID: mdl-35443795

Assuntos

Músculo Liso Vascular; Fator de Crescimento Transformador beta; Animais; Aorta/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Músculo Liso Vascular/metabolismo; Miócitos de Músculo Liso/metabolismo; Proteínas Serina-Treonina Quinases; Receptores de Fatores de Crescimento Transformadores beta/genética; Receptores de Fatores de Crescimento Transformadores beta/metabolismo; Fator de Crescimento Transformador beta/metabolismo; Fator de Crescimento Transformador beta1/metabolismo

Palavras-chave

aorta; genetic techniques; genotype; intercellular signaling peptides and proteins; myocytes, smooth muscle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Músculo Liso Vascular Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Arterioscler Thromb Vasc Biol Assunto da revista: ANGIOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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