Establishment of antitick efficacy of a phytoformulation prepared from Annona squamosa leaf extracts for the management of acaricide resistant tick infestations on cattle.
Acta Trop
; 233: 106463, 2022 Sep.
Article
em En
| MEDLINE
| ID: mdl-35460645
To combat the problem of acaricide resistance in ticks, efforts have been made to develop eco-friendly herbal acaricides which are safe for animal use with no possibilities of evoking environment and residual toxicity. In the present study, the acaricidal properties of a commonly available plant, Annona squamosa have been established to develop a novel antitick phytoformulation using leaf extract, suitable solvents and emulsifier for managing resistant tick infestations in animals. The quality control of the safe and stable phytoformulation using Rutin as a major constituent was maintained by HPTLC profiling. Several phytformulations (A-E) were prepared and formulation 'C' is identifried as the most effective showing 52.5-75% antitick activity against in vitro treated resistant strains of R. microplus (IVRI-IV and V) with 33.8-40.2% inhibition of oviposition while 65-85% mortality against multiacaricide resistant field populations. The phytoformulation provided 70.4% efficacy after first larval challenge in experimentally infested animals. The field efficacy of the formulation in different multilocational field trials was 68.53-77.8%. The detail antitick efficacy of the formulation along with safety and stability are explained as a component of antitck technology to manage resistant tick problem in livestock.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infestações por Carrapato
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Extratos Vegetais
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Doenças dos Bovinos
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Annona
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Rhipicephalus
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Acaricidas
Limite:
Animals
Idioma:
En
Revista:
Acta Trop
Ano de publicação:
2022
Tipo de documento:
Article