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Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
Fass, Daniel M; Lewis, Michael C; Ahmad, Rushdy; Szucs, Matthew J; Zhang, Qiangge; Fleishman, Morgan; Wang, Dongqing; Kim, Myung Jong; Biag, Jonathan; Carr, Steven A; Scolnick, Edward M; Premont, Richard T; Haggarty, Stephen J.
Afiliação
  • Fass DM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA, 02142, USA.
  • Lewis MC; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Departments of Neurology & Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
  • Ahmad R; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA, 02142, USA.
  • Szucs MJ; Sage Therapeutics, Cambridge, MA, USA.
  • Zhang Q; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA.
  • Fleishman M; Wyss Institute at Harvard University, Boston, MA, USA.
  • Wang D; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA.
  • Kim MJ; Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, CO, USA.
  • Biag J; McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Carr SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA, 02142, USA.
  • Scolnick EM; McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Premont RT; McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Haggarty SJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA, 02142, USA.
Mol Psychiatry ; 27(8): 3272-3285, 2022 08.
Article em En | MEDLINE | ID: mdl-35505090
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Proteínas de Ciclo Celular / Proteínas Ativadoras de GTPase Limite: Animals Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Proteínas de Ciclo Celular / Proteínas Ativadoras de GTPase Limite: Animals Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos