Role of sperm DNA damage in creating de-novo mutations in human offspring: the 'post-meiotic oocyte collusion' hypothesis.

Aitken, Robert John

Aitken, Robert John.

Afiliação

Aitken RJ; Priority Research Centre for Reproductive Science, College of Engineering, Science and Environment, The University of Newcastle, Callaghan New South Wales, Australia; Hunter Medical Research Institute, New Lambton Heights New South Wales, Australia. Electronic address: john.aitken@newcastle.edu.au.

Reprod Biomed Online ; 45(1): 109-124, 2022 07.

Article em En | MEDLINE | ID: mdl-35513995

Assuntos

Sêmen; Espermatozoides; Dano ao DNA; Humanos; Masculino; Mutação; Oócitos; Espermatozoides/metabolismo

Palavras-chave

DNA damage; DNA repair; De-novo mutations; Oocyte; Oxidative stress; Spermatozoa

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sêmen / Espermatozoides Limite: Humans / Male Idioma: En Revista: Reprod Biomed Online Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2022 Tipo de documento: Article

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