Mitigating analyte to stable isotope labelled internal standard cross-signal contribution in quantitative liquid chromatography-tandem mass spectrometry.

Radovanovic, Mirjana; Jones, Graham; Day, Richard O; Galettis, Peter; Norris, Ross L G

Radovanovic, Mirjana; Jones, Graham; Day, Richard O; Galettis, Peter; Norris, Ross L G.

Afiliação

Radovanovic M; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia.
Jones G; SydPath, St Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
Day RO; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia.
Galettis P; SydPath, St Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
Norris RLG; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia.

J Mass Spectrom Adv Clin Lab ; 24: 57-64, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35520954

Palavras-chave

13C4-FLX, 13C4 flucloxacillin; Cross-signal contribution; FLX, flucloxacillin; Isotopic distribution; K3-EDTA, potassium ethylenediaminetetraacetic acid; LC-MS/MS; LC-MS/MS, liquid chromatography-tandem mass spectrometry; LLOQ, lower limit of quantification; MRM, multiple reaction monitoring; MS1, quadrupole 1; MS2, quadrupole 2; Q1, first quadrupole; Q3, third quadrupole; QC, quality control; SIL-IS, stable isotope labelled internal standard; Stable isotope labelled internal standard; ULOQ, upper limit of quantification

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Mass Spectrom Adv Clin Lab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália

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