Your browser doesn't support javascript.
loading
To beat the heat - engineering of the most thermostable pyruvate decarboxylase to date.
Sutiono, Samuel; Satzinger, Katharina; Pick, André; Carsten, Jörg; Sieber, Volker.
Afiliação
  • Sutiono S; Chair of Chemistry of Biogenic Resources, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich Schulgasse 16 94315 Straubing Germany sieber@tum.de.
  • Satzinger K; Chair of Chemistry of Biogenic Resources, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich Schulgasse 16 94315 Straubing Germany sieber@tum.de.
  • Pick A; Chair of Chemistry of Biogenic Resources, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich Schulgasse 16 94315 Straubing Germany sieber@tum.de.
  • Carsten J; Chair of Chemistry of Biogenic Resources, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich Schulgasse 16 94315 Straubing Germany sieber@tum.de.
  • Sieber V; Catalytic Research Center, Technical University of Munich Ernst-Otto-Fischer-Straße 1 85748 Garching Germany.
RSC Adv ; 9(51): 29743-29746, 2019 Sep 18.
Article em En | MEDLINE | ID: mdl-35531508
ABSTRACT
Pyruvate decarboxylase (PDC) is a key enzyme for the production of ethanol at high temperatures and for cell-free butanol synthesis. Thermostable, organic solvent stable PDC was evolved from bacterial PDCs. The new variant shows >1500-fold-improved half-life at 75 °C and >5000-fold-increased half-life in the presence of 9 vol% butanol at 50 °C.
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: RSC Adv Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: RSC Adv Ano de publicação: 2019 Tipo de documento: Article