First Report of a Paediatric Collision Tumour in the Liver Recognised After Liver Transplantation: Blissful Ignorance Has Benefits!
J Clin Exp Hepatol
; 12(2): 696-700, 2022.
Article
em En
| MEDLINE
| ID: mdl-35535070
ABSTRACT
Liver tumours are uncommon in the paediatric population, constituting 1-2 % of all paediatric tumours and 4% of all paediatric liver tumours. Hepatoblastoma followed by hepatocellular carcinoma is the most common tumours in this age group. Simultaneous development of two discrete liver tumours of distinct histologies (collision tumour) has been occasionally reported in adults but never in children. We hereby present the first reported case of hepatic collision tumours (hepatocellular carcinoma and cholangiocarcinoma) in the explant liver of a child who underwent living donor liver transplantation for end-stage liver disease and severe hepatopulmonary syndrome. The manuscript describes the clinical, radiological and histopathological findings of this case and also highlights the dilemma associated with management of this case had the diagnosis been made in the preoperative setting and also about the proposed management plan for this case in the postoperative period.
AFP, alpha fetoprotein; CA 19-9, carbohydrate antigen; CC, cholangiocarcinoma; CECT, contrast-enhanced computed tomography; CPAP, continuous positive airway pressure; Ck, cytokeratin; HCC, hepatocellular carcinoma; HPS, hepatopulmonary syndrome; LDLT, living donor liver transplantation; LT, liver transplant; MAA scan, macro albumin aggregate scan; PELD, pediataric end-stage liver disease score; POD, postoperative day; UCSF, University of California San Francisco; UGI, upper gastrointestinal; cholangiocarcinoma; collision tumour; hepatocellular carcinoma; liver transplant; paediatric liver transplant
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Base de dados:
MEDLINE
Idioma:
En
Revista:
J Clin Exp Hepatol
Ano de publicação:
2022
Tipo de documento:
Article
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Índia