Tumor mutational burden presents limiting effects on predicting the efficacy of immune checkpoint inhibitors and prognostic assessment in adrenocortical carcinoma.

Xu, Fangshi; Guan, Yibing; Zhang, Peng; Xue, Li; Ma, Yubo; Gao, Mei; Chong, Tie; Ren, Bin-Cheng

Tumor mutational burden presents limiting effects on predicting the efficacy of immune checkpoint inhibitors and prognostic assessment in adrenocortical carcinoma.

Xu, Fangshi; Guan, Yibing; Zhang, Peng; Xue, Li; Ma, Yubo; Gao, Mei; Chong, Tie; Ren, Bin-Cheng.

Afiliação

Xu F; Department of Medicine, Xi'an Jiaotong University, No. 76, Yanta West Road, Xi'an, 710061, Shaanxi, China.
Guan Y; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Five Road, Xi'an, 710000, Shaanxi Province, China.
Zhang P; Department of Medicine, Xi'an Jiaotong University, No. 76, Yanta West Road, Xi'an, 710061, Shaanxi, China.
Xue L; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Five Road, Xi'an, 710000, Shaanxi Province, China.
Ma Y; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Five Road, Xi'an, 710000, Shaanxi Province, China.
Gao M; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Five Road, Xi'an, 710000, Shaanxi Province, China.
Chong T; Department of Medicine, Xi'an Jiaotong University, No. 76, Yanta West Road, Xi'an, 710061, Shaanxi, China.
Ren BC; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Five Road, Xi'an, 710000, Shaanxi Province, China.

BMC Endocr Disord ; 22(1): 130, 2022 May 14.

Article em En | MEDLINE | ID: mdl-35568842

Assuntos

Neoplasias do Córtex Suprarrenal; Carcinoma Adrenocortical; Neoplasias do Córtex Suprarrenal/tratamento farmacológico; Neoplasias do Córtex Suprarrenal/genética; Carcinoma Adrenocortical/tratamento farmacológico; Carcinoma Adrenocortical/genética; Biomarcadores Tumorais/genética; Humanos; Inibidores de Checkpoint Imunológico/uso terapêutico; Mutação; Prognóstico; Microambiente Tumoral/genética

Palavras-chave

Adrenocortical carcinoma; Immune checkpoint inhibitors; Immune microenvironment; Prognosis; Tumor mutational burden

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Córtex Suprarrenal / Carcinoma Adrenocortical Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Endocr Disord Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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