[Aspergillus mediastinitis following post-immunotherapy lobectomy for oligometastatic lung]. / Médiastinite à Aspergillus après lobectomie post immunothérapie pour un cancer du poumon oligométastatique.
Rev Mal Respir
; 39(5): 498-501, 2022 May.
Article
em Fr
| MEDLINE
| ID: mdl-35570033
ABSTRACT
The relationship between infectious disease and therapy with immune checkpoint inhibitors remains unknown. We report the case of a 50-year-old woman with metastatic lung adenocarcinoma who responded remarkably well to immunotherapy and underwent upper right lobectomy. Three weeks after hospital discharge, she was readmitted for severe dyspnea due to mainstem bronchus compression by mediastinal mass. Histological analysis of transbronchial needle aspiration revealed A. fumigatus. After six months of voriconazole regimen, her symptoms improved with the regression of bronchial compression. Postoperative progression of pseudo-tumoral mass in patients treated with long-term immunotherapy may be related to opportunistic infectious disease and requires investigation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pulmonares
/
Mediastinite
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Female
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Humans
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Middle aged
Idioma:
Fr
Revista:
Rev Mal Respir
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
França