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Prediction of Maternal and Fetal Doravirine Exposure by Integrating Physiologically Based Pharmacokinetic Modeling and Human Placenta Perfusion Experiments.
Bukkems, V E; van Hove, H; Roelofsen, D; Freriksen, J J M; van Ewijk-Beneken Kolmer, E W J; Burger, D M; van Drongelen, J; Svensson, E M; Greupink, R; Colbers, A.
Afiliação
  • Bukkems VE; Department of Pharmacy, Radboud Institute of Health Sciences (RIHS), Radboud university medical center, Nijmegen, the Netherlands. Vera.Bukkems@radboudumc.nl.
  • van Hove H; Department of Pharmacology and Toxicology, Radboud university medical center, Nijmegen, The Netherlands.
  • Roelofsen D; Department of Pharmacy, Radboud Institute of Health Sciences (RIHS), Radboud university medical center, Nijmegen, the Netherlands.
  • Freriksen JJM; Department of Pharmacology and Toxicology, Radboud university medical center, Nijmegen, The Netherlands.
  • van Ewijk-Beneken Kolmer EWJ; Department of Pharmacology and Toxicology, Radboud university medical center, Nijmegen, The Netherlands.
  • Burger DM; Department of Pharmacy, Radboud Institute of Health Sciences (RIHS), Radboud university medical center, Nijmegen, the Netherlands.
  • van Drongelen J; Department of Pharmacy, Radboud Institute of Health Sciences (RIHS), Radboud university medical center, Nijmegen, the Netherlands.
  • Svensson EM; Department of Obstetrics and Gynaecology, Radboud university medical center, Nijmegen, The Netherlands.
  • Greupink R; Department of Pharmacy, Radboud Institute of Health Sciences (RIHS), Radboud university medical center, Nijmegen, the Netherlands.
  • Colbers A; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Clin Pharmacokinet ; 61(8): 1129-1141, 2022 08.
Article em En | MEDLINE | ID: mdl-35579825

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Troca Materno-Fetal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Clin Pharmacokinet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Troca Materno-Fetal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Clin Pharmacokinet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda