LXR activation ameliorates high glucose stress-induced aberrant mitochondrial dynamics via downregulation of Calpain1 expression in H9c2 cardiomyoblasts.

Lin, Jiejin; Wang, Fengdan; Jiang, Ge; Zhang, Tiantian; Zhang, Junfeng; He, Qing; Fan, Yuqi

Lin, Jiejin; Wang, Fengdan; Jiang, Ge; Zhang, Tiantian; Zhang, Junfeng; He, Qing; Fan, Yuqi.

Afiliação

Lin J; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Wang F; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Jiang G; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Zhang T; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Zhang J; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
He Q; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. Electronic address: dr.heqing@outlook.com.
Fan Y; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. Electronic address: fanyq1770@sh9hospital.org.cn.

Biochem Biophys Res Commun ; 614: 145-152, 2022 07 23.

Article em En | MEDLINE | ID: mdl-35597151

Assuntos

Calpaína; Diabetes Mellitus Experimental; Cardiomiopatias Diabéticas; Glucose; Receptores X do Fígado; Dinâmica Mitocondrial; Animais; Apoptose; Calpaína/genética; Calpaína/metabolismo; Diabetes Mellitus Experimental/metabolismo; Cardiomiopatias Diabéticas/metabolismo; Regulação para Baixo; Glucose/metabolismo; Receptores X do Fígado/genética; Receptores X do Fígado/metabolismo; Dinâmica Mitocondrial/genética; Dinâmica Mitocondrial/fisiologia; Miócitos Cardíacos/metabolismo; Estresse Oxidativo; Ratos

Palavras-chave

Calpain1; Diabetes; Liver X receptor; Mitochondrial dynamics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calpaína / Diabetes Mellitus Experimental / Cardiomiopatias Diabéticas / Dinâmica Mitocondrial / Receptores X do Fígado / Glucose Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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