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Serum uric acid in patients with ST-segment elevation myocardial infarction: An innocent bystander or leading actor?
Kajana, Vilma; Massaro, Gianluca; Somaschini, Alberto; Cornara, Stefano; Demarchi, Andrea; Nardella, Elisabetta; Nicoletti, Alberto; Sangiorgi, Giuseppe Massimo; Mandurino-Mirizzi, Alessandro.
Afiliação
  • Kajana V; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Massaro G; Division of Cardiology, University Hospital "Tor Vergata", Rome, Italy.
  • Somaschini A; Division of Cardiology and Cardiac Intensive Care Unit, San Paolo Hospital, Savona, Italy.
  • Cornara S; Division of Cardiology and Cardiac Intensive Care Unit, San Paolo Hospital, Savona, Italy.
  • Demarchi A; Cardiocentro Ticino, Lugano, Switzerland.
  • Nardella E; Internal Medicine, Gastroenterology and Hepatology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
  • Nicoletti A; Internal Medicine, Gastroenterology and Hepatology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
  • Sangiorgi GM; Division of Cardiology, University Hospital "Tor Vergata", Rome, Italy.
  • Mandurino-Mirizzi A; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. Electronic address: ale.mandurinomirizzi@gmail.com.
Nutr Metab Cardiovasc Dis ; 32(7): 1583-1589, 2022 07.
Article em En | MEDLINE | ID: mdl-35597708
ABSTRACT
Elevated serum uric acid (SUA) levels have been associated with several cardiovascular risk factors and the progression of coronary artery disease. In the setting of acute myocardial infarction, increasing evidence suggests that high SUA levels could be related to adverse outcomes. Interestingly elevated SUA levels have been linked to endothelial dysfunction, inflammation and oxidative stress. The aim of this review is to discuss the potential negative effects of SUA in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention, analyzing the possible underlying pathophysiological mechanisms.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Intervenção Coronária Percutânea / Infarto do Miocárdio com Supradesnível do Segmento ST / Infarto do Miocárdio Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nutr Metab Cardiovasc Dis Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / CIENCIAS DA NUTRICAO / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Intervenção Coronária Percutânea / Infarto do Miocárdio com Supradesnível do Segmento ST / Infarto do Miocárdio Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nutr Metab Cardiovasc Dis Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / CIENCIAS DA NUTRICAO / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália