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Effect of Metformin vs Placebo on Invasive Disease-Free Survival in Patients With Breast Cancer: The MA.32 Randomized Clinical Trial.
Goodwin, Pamela J; Chen, Bingshu E; Gelmon, Karen A; Whelan, Timothy J; Ennis, Marguerite; Lemieux, Julie; Ligibel, Jennifer A; Hershman, Dawn L; Mayer, Ingrid A; Hobday, Timothy J; Bliss, Judith M; Rastogi, Priya; Rabaglio-Poretti, Manuela; Mukherjee, Som D; Mackey, John R; Abramson, Vandana G; Oja, Conrad; Wesolowski, Robert; Thompson, Alastair M; Rea, Daniel W; Stos, Paul M; Shepherd, Lois E; Stambolic, Vuk; Parulekar, Wendy R.
Afiliação
  • Goodwin PJ; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Chen BE; Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada.
  • Gelmon KA; Department of Medicine, University of British Columbia, BC Cancer Agency, Vancouver, Canada.
  • Whelan TJ; Department of Radiation Oncology, McMaster University, Juravinski Cancer Centre, Hamilton, Ontario, Canada.
  • Ennis M; Applied Statistician, Markham, Ontario, Canada.
  • Lemieux J; Department of Hematology Research, CHU de Québec-Université Laval, Québec, Québec, Canada.
  • Ligibel JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Hershman DL; Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.
  • Mayer IA; Department of Medicine, Vanderbilt University, Nashville, Tennessee.
  • Hobday TJ; Department of Oncology, Mayo Clinic, Rochester, Minnesota.
  • Bliss JM; Division of Clinical Studies, ICR-CTSU, Institute of Cancer Research United Kingdom, London, United Kingdom.
  • Rastogi P; Department of Medicine, NRG Oncology and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
  • Rabaglio-Poretti M; Department of Medical Oncology, IBCSG and Department of Oncology, Bern University Hospital, University of Bern, Berne, Switzerland.
  • Mukherjee SD; Department of Oncology, Juravinski Cancer Center, McMaster University, Hamilton, Ontario, Canada.
  • Mackey JR; Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Canada.
  • Abramson VG; Department of Medicine, Vanderbilt University, Nashville, Tennessee.
  • Oja C; Department of Medicine, University of British Columbia, BC Cancer Agency, Vancouver, Canada.
  • Wesolowski R; Department of Internal Medicine, James Cancer Hospital, Ohio State Comprehensive Cancer Center, Columbus, Ohio.
  • Thompson AM; Department of Surgery, Baylor College of Medicine, Houston, Texas.
  • Rea DW; School of Cancer and Genomic Science, Cancer Research UK Clinical Trials Unit (CRCTU), Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Stos PM; Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada.
  • Shepherd LE; Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada.
  • Stambolic V; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Parulekar WR; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
JAMA ; 327(20): 1963-1973, 2022 05 24.
Article em En | MEDLINE | ID: mdl-35608580
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Metformina / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Metformina / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá