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[Influence of processing factors on honey-fried Codonopsis Radix].
Tang, Ya-Nan; Han, Xi-Tao; Liu, Zi-Qin; Bao, Li-Yuan; Wang, Hong-Yue; Liu, Kai-Yang; Han, Shu; Li, Wei-Fei; Hu, Fang-di; DU, Hong.
Afiliação
  • Tang YN; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Han XT; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Liu ZQ; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Bao LY; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Wang HY; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Liu KY; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Han S; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
  • Li WF; China Beijing Tongrentang (Group) Co., Ltd. Beijing 100062, China.
  • Hu FD; School of Pharmacy, Lanzhou University Lanzhou 730000, China.
  • DU H; School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
Zhongguo Zhong Yao Za Zhi ; 47(11): 2975-2981, 2022 Jun.
Article em Zh | MEDLINE | ID: mdl-35718519
ABSTRACT
The present study investigated the influence of heating and honey addition on the appearance, chemical component content, and pharmacological activity of Codonopsis Radix decoction pieces in the honey-frying process, and explored the processing mechanism of honey-fried Codonopsis Radix. The color, sweetness, and content of macromolecular components(e.g., oligosaccharides and polysaccharides) and small molecular components(e.g., lobetyolin and atractylenolide Ⅲ) of raw Codonopsis Radix, fried Codonopsis Radix, honey-mixed Codonopsis Radix, and honey-fried Codonopsis Radix were determined, and the antioxidant activities in vitro of their water extract, polysaccharide extract, and oligosaccharide extract were compared. The results showed that in terms of color and sweetness, compared with the raw Codonopsis Radix, the fried Codonopsis Radix slightly changed, the honey-mixed Codonopsis Radix changed significantly, and the honey-fried Codonopsis Radix changed with high significance. In terms of the content of lobetyolin, atractylenolide Ⅲ, and polysaccharides, the samples were ranked as raw Codonopsis Radix > fried Codonopsis Radix > honey-mixed Codonopsis Radix > honey-fried Codonopsis Radix, which indicated that heating and honey addition could reduce the content of these three components. In terms of the content of oligosaccharides, the samples were ranked as honey-fried Codonopsis Radix ≈ honey-mixed Codonopsis Radix > fried Codonopsis Radix ≈ raw Codonopsis Radix, indicating that honey addition could increase the content of oligosaccharides. In terms of antioxidant activity in vitro, ABTS radical scavenging ability of water extract, polysaccharides, and oligosaccharides of honey-fried Codonopsis Radix was most potent, while the change of antioxidant activity in vitro of each extract in the other three processed products was different. In short, both heating and honey addition can affect the appearance, chemical component content, and antioxidant activity in vitro of Codonopsis Radix decoction pieces, but the effect of the combination of the two factors is the best. The comprehensive analysis of the effects of heating and honey addition on Codonopsis Radix decoction pieces indicates that honey addition followed by heating at high temperature is the necessary condition for honey-fried Codonopsis Radix to enhance its activity.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Codonopsis / Mel Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Codonopsis / Mel Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China