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Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein-VDAC complexation as a potential therapeutic target for Parkinson's disease treatment.
Rajendran, Megha; Queralt-Martín, María; Gurnev, Philip A; Rosencrans, William M; Rovini, Amandine; Jacobs, Daniel; Abrantes, Kaitlin; Hoogerheide, David P; Bezrukov, Sergey M; Rostovtseva, Tatiana K.
Afiliação
  • Rajendran M; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Queralt-Martín M; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Gurnev PA; Laboratory of Molecular Biophysics, Department of Physics, Universitat Jaume I, Castellón, 12071, Spain.
  • Rosencrans WM; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Rovini A; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Jacobs D; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Abrantes K; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Hoogerheide DP; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
  • Bezrukov SM; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA.
  • Rostovtseva TK; Section On Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bldg. 29B, Room 1G09, Bethesda, MD, 20892, USA.
Cell Mol Life Sci ; 79(7): 368, 2022 Jun 19.
Article em En | MEDLINE | ID: mdl-35718804

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína Limite: Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína Limite: Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos