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PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages.
Yamaguchi, Yukiko; Gibson, Jackson; Ou, Kevin; Lopez, Lupita S; Ng, Rachel H; Leggett, Neena; Jonsson, Vanessa D; Zarif, Jelani C; Lee, Peter P; Wang, Xiuli; Martinez, Catalina; Dorff, Tanya B; Forman, Stephen J; Priceman, Saul J.
Afiliação
  • Yamaguchi Y; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Gibson J; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Ou K; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Lopez LS; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Ng RH; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Leggett N; Department of Bioengineering, University of Washington, Seattle, Washington, USA.
  • Jonsson VD; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Zarif JC; Department of Applied Mathematics, University of California, Santa Cruz, California, USA.
  • Lee PP; Department of Biomolecular Engineering, University of California, Santa Cruz, California, USA.
  • Wang X; Department of Oncology, Johns Hopkins University School of Medicine and The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
  • Martinez C; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
  • Dorff TB; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA.
  • Forman SJ; Department of Clinical and Translational Project Development, City of Hope, Duarte, CA, USA.
  • Priceman SJ; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California, USA.
J Immunother Cancer ; 10(6)2022 06.
Article em En | MEDLINE | ID: mdl-35738799

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígeno B7-H1 / Imunoterapia / Macrófagos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígeno B7-H1 / Imunoterapia / Macrófagos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos