Microbiome-associated human genetic variants impact phenome-wide disease risk.

Markowitz, Robert H George; LaBella, Abigail Leavitt; Shi, Mingjian; Rokas, Antonis; Capra, John A; Ferguson, Jane F; Mosley, Jonathan D; Bordenstein, Seth R

Markowitz, Robert H George; LaBella, Abigail Leavitt; Shi, Mingjian; Rokas, Antonis; Capra, John A; Ferguson, Jane F; Mosley, Jonathan D; Bordenstein, Seth R.

Afiliação

Markowitz RHG; Vanderbilt Microbiome Innovation Center, Vanderbilt University, Nashville, TN 37232.
LaBella AL; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232.
Shi M; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232.
Rokas A; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232.
Capra JA; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232.
Ferguson JF; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143.
Mosley JD; Bakar Computational Health Sciences Institute, University of California, San Francisco, CA 94143.
Bordenstein SR; Vanderbilt Microbiome Innovation Center, Vanderbilt University, Nashville, TN 37232.

Proc Natl Acad Sci U S A ; 119(26): e2200551119, 2022 06 28.

Article em En | MEDLINE | ID: mdl-35749358

Assuntos

Doença; Microbioma Gastrointestinal; Variação Genética; Doença/genética; Genoma Humano; Humanos; Fenômica; Fenótipo

Palavras-chave

PheWAS; gut microbiome; hostmicrobe interactions; microbiome-associated disease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Doença / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Observational_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article

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