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Fragment Screening Yields a Small-Molecule Stabilizer of 14-3-3 Dimers That Modulates Client Protein Interactions.
Brink, Hendrik J; Riemens, Rick; Thee, Stephanie; Beishuizen, Berend; da Costa Pereira, Daniel; Wijtmans, Maikel; de Esch, Iwan; Smit, Martine J; de Boer, Albertus H.
Afiliação
  • Brink HJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • Riemens R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • Thee S; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • Beishuizen B; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • da Costa Pereira D; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • Wijtmans M; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • de Esch I; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • Smit MJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
  • de Boer AH; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), De Boelelaan 1108, 1081 HZ, Amsterdam (The, Netherlands.
Chembiochem ; 23(17): e202200178, 2022 09 05.
Article em En | MEDLINE | ID: mdl-35767695

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas 14-3-3 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas 14-3-3 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda