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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer.
Joanito, Ignasius; Wirapati, Pratyaksha; Zhao, Nancy; Nawaz, Zahid; Yeo, Grace; Lee, Fiona; Eng, Christine L P; Macalinao, Dominique Camat; Kahraman, Merve; Srinivasan, Harini; Lakshmanan, Vairavan; Verbandt, Sara; Tsantoulis, Petros; Gunn, Nicole; Venkatesh, Prasanna Nori; Poh, Zhong Wee; Nahar, Rahul; Oh, Hsueh Ling Janice; Loo, Jia Min; Chia, Shumei; Cheow, Lih Feng; Cheruba, Elsie; Wong, Michael Thomas; Kua, Lindsay; Chua, Clarinda; Nguyen, Andy; Golovan, Justin; Gan, Anna; Lim, Wan-Jun; Guo, Yu Amanda; Yap, Choon Kong; Tay, Brenda; Hong, Yourae; Chong, Dawn Qingqing; Chok, Aik-Yong; Park, Woong-Yang; Han, Shuting; Chang, Mei Huan; Seow-En, Isaac; Fu, Cherylin; Mathew, Ronnie; Toh, Ee-Lin; Hong, Lewis Z; Skanderup, Anders Jacobsen; DasGupta, Ramanuj; Ong, Chin-Ann Johnny; Lim, Kiat Hon; Tan, Emile K W; Koo, Si-Lin; Leow, Wei Qiang.
Afiliação
  • Joanito I; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Wirapati P; Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Zhao N; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Nawaz Z; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Yeo G; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Lee F; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Eng CLP; National Cancer Centre, Singapore, Singapore.
  • Macalinao DC; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Kahraman M; National Cancer Centre, Singapore, Singapore.
  • Srinivasan H; National Cancer Centre, Singapore, Singapore.
  • Lakshmanan V; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Verbandt S; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Tsantoulis P; National Cancer Centre, Singapore, Singapore.
  • Gunn N; National Cancer Centre, Singapore, Singapore.
  • Venkatesh PN; Molecular Digestive Oncology, Department of Oncology, Katholieke Universiteit Leuven, Leuven, Belgium.
  • Poh ZW; Hôpitaux Universitaires de Genève, Geneva, Switzerland.
  • Nahar R; University of Geneva, Geneva, Switzerland.
  • Oh HLJ; National Cancer Centre, Singapore, Singapore.
  • Loo JM; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Chia S; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Cheow LF; Duke-National University of Singapore Medical School, Singapore, Singapore.
  • Cheruba E; MSD International GmbH (Singapore Branch), Singapore, Singapore.
  • Wong MT; MSD International GmbH (Singapore Branch), Singapore, Singapore.
  • Kua L; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Chua C; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Nguyen A; National University of Singapore, Singapore, Singapore.
  • Golovan J; National University of Singapore, Singapore, Singapore.
  • Gan A; MSD International GmbH (Singapore Branch), Singapore, Singapore.
  • Lim WJ; National Cancer Centre, Singapore, Singapore.
  • Guo YA; National Cancer Centre, Singapore, Singapore.
  • Yap CK; NantOmics, Rockville, MD, USA.
  • Tay B; NantOmics, Rockville, MD, USA.
  • Hong Y; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Chong DQ; National Cancer Centre, Singapore, Singapore.
  • Chok AY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Park WY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Han S; National Cancer Centre, Singapore, Singapore.
  • Chang MH; Samsung Genome Institute, Samsung Medical Center, Seoul, Korea.
  • Seow-En I; National Cancer Centre, Singapore, Singapore.
  • Fu C; Duke-National University of Singapore Medical School, Singapore, Singapore.
  • Mathew R; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • Toh EL; Samsung Genome Institute, Samsung Medical Center, Seoul, Korea.
  • Hong LZ; National Cancer Centre, Singapore, Singapore.
  • Skanderup AJ; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • DasGupta R; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • Ong CJ; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • Lim KH; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • Tan EKW; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.
  • Koo SL; EL Toh Colorectal & Minimally Invasive Surgery, Singapore, Singapore.
  • Leow WQ; MSD International GmbH (Singapore Branch), Singapore, Singapore.
Nat Genet ; 54(7): 963-975, 2022 07.
Article em En | MEDLINE | ID: mdl-35773407
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Epiteliais e Glandulares Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Singapura
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Epiteliais e Glandulares Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Singapura