Efficacy of the Fluocinolone Acetonide (Yutiq) Intravitreal Implant as Monotherapy for Uveitis.
Ocul Immunol Inflamm
; 31(8): 1603-1607, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-35793136
ABSTRACT
PURPOSE:
To evaluate the efficacy of the fluocinolone acetonide intravitreal implant (Yutiq) as monotherapy for uveitis.DESIGN:
Retrospective cohort study.PARTICIPANTS:
Patients at a single academic health-care institution.METHODS:
Medical record review of patients with non-infectious uveitis actively suppressed on an alternative anti-inflammatory regimen who received a fluocinolone acetonide implant. The primary outcome was continued control of inflammation based on clinical examination, optical coherence tomography, and fluorescein angiography.RESULTS:
Thirteen patients (19 eyes) received an implant. Median follow-up was 6 months. Uveitis control was achieved in 14 eyes (74%), though three (21%) required a topical steroid after insertion. The remaining five eyes (26%) required additional intraocular treatments.CONCLUSION:
The fluocinolone acetonide implant may not suffice as monotherapy for all patients with uveitis, but it may be effective as an adjunctive treatment. We propose a clinical workflow for the selection and treatment of patients who may benefit from it.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Uveíte
/
Glucocorticoides
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
En
Revista:
Ocul Immunol Inflamm
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos