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Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.
Döhner, Hartmut; Wei, Andrew H; Appelbaum, Frederick R; Craddock, Charles; DiNardo, Courtney D; Dombret, Hervé; Ebert, Benjamin L; Fenaux, Pierre; Godley, Lucy A; Hasserjian, Robert P; Larson, Richard A; Levine, Ross L; Miyazaki, Yasushi; Niederwieser, Dietger; Ossenkoppele, Gert; Röllig, Christoph; Sierra, Jorge; Stein, Eytan M; Tallman, Martin S; Tien, Hwei-Fang; Wang, Jianxiang; Wierzbowska, Agnieszka; Löwenberg, Bob.
Afiliação
  • Döhner H; Department of Internal Medicine III, Ulm University Hospital, Ulm, Germany.
  • Wei AH; Department of Haematology, Peter MacCallum Cancer Centre, Royal Melbourne Hospital and University of Melbourne, Melbourne, Australia.
  • Appelbaum FR; University of Washington and the Fred Hutchinson Cancer Research Center, Seattle, WA.
  • Craddock C; Centre for Clinical Haematology, Queen Elizabeth Hospital, University of Birminham, Birmingham, UK.
  • DiNardo CD; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Dombret H; Department of Hematology, Saint-Louis Institute for Research, Université de Paris, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • Ebert BL; Dana-Farber Cancer Institute, Boston, MA.
  • Fenaux P; Service d'Hématologie Séniors, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • Godley LA; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
  • Hasserjian RP; Department of Pathology, Massachusetts General Hospital, Boston, MA.
  • Larson RA; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, IL.
  • Levine RL; Human Oncology and Pathogenesis Program and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Miyazaki Y; Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.
  • Niederwieser D; University of Leipzig, Leipzig, Germany.
  • Ossenkoppele G; Department of Haematology, Amsterdam UMC, Location VU University Medical Center, Amsterdam, The Netherlands.
  • Röllig C; Department of Internal Medicine I, University Hospital Carl Gustav Carus TU Dresden, Dresden, Germany.
  • Sierra J; Hematology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain.
  • Stein EM; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York.
  • Tallman MS; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York.
  • Tien HF; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
  • Wang J; Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
  • Wierzbowska A; Department of Hematology, Medical University of Lodz, Lodz, Poland; and.
  • Löwenberg B; Department of Hematology, Erasmus University Medical Center Rotterdam and Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Blood ; 140(12): 1345-1377, 2022 09 22.
Article em En | MEDLINE | ID: mdl-35797463
ABSTRACT
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults are widely recognized among physicians and investigators. There have been major advances in our understanding of AML, including new knowledge about the molecular pathogenesis of AML, leading to an update of the disease classification, technological progress in genomic diagnostics and assessment of measurable residual disease, and the successful development of new therapeutic agents, such as FLT3, IDH1, IDH2, and BCL2 inhibitors. These advances have prompted this update that includes a revised ELN genetic risk classification, revised response criteria, and treatment recommendations.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Antineoplásicos Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Antineoplásicos Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha