MicroRNA-21-5p promotes mucosal type 2 inflammation via regulating GLP1R/IL-33 signaling in chronic rhinosinusitis with nasal polyps.

Luan, Ge; Wang, Ming; Yuan, Jing; Bu, Xiangting; Wang, Yang; Ying, Sun; Wang, Chengshuo; Zhang, Luo

Luan, Ge; Wang, Ming; Yuan, Jing; Bu, Xiangting; Wang, Yang; Ying, Sun; Wang, Chengshuo; Zhang, Luo.

Afiliação

Luan G; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Wang M; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Yuan J; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Bu X; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Wang Y; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Ying S; Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. Electronic address: ying.sun@ccmu.edu.cn.
Wang C; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China. Electronic address: wangcs830@126.com.
Zhang L; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China; Department of Allergy, Beijing TongRen

J Allergy Clin Immunol ; 150(6): 1460-1475, 2022 12.

Article em En | MEDLINE | ID: mdl-35835254

Assuntos

MicroRNAs; Pólipos Nasais; Humanos; Camundongos; Animais; Pólipos Nasais/genética; Interleucina-33/genética; Receptor do Peptídeo Semelhante ao Glucagon 1; Camundongos Knockout; MicroRNAs/genética

Palavras-chave

Chronic rhinosinusitis with nasal polyps; glucagon-like peptide-1 receptor; microRNA-21-5p; type 2 inflammation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pólipos Nasais / MicroRNAs Limite: Animals / Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google