The effect of citalopram treatment on amyloid-ß precursor protein processing and oxidative stress in human hNSC-derived neurons.

Elsworthy, R J; Crowe, J A; King, M C; Dunleavy, C; Fisher, E; Ludlam, A; Parri, H R; Hill, E J; Aldred, S

Elsworthy, R J; Crowe, J A; King, M C; Dunleavy, C; Fisher, E; Ludlam, A; Parri, H R; Hill, E J; Aldred, S.

Afiliação

Elsworthy RJ; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK. r.j.elsworthy@bham.ac.uk.
Crowe JA; Centre for Human Brain Health (CHBH), University of Birmingham, Edgbaston, Birmingham, UK. r.j.elsworthy@bham.ac.uk.
King MC; School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham, UK.
Dunleavy C; Department of Clinical Sciences, Division of Neurology, Lund Stem Cell Centre, Faculty of Medicine, Lund University, Lund, Sweden.
Fisher E; School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham, UK.
Ludlam A; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Parri HR; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Hill EJ; Department of Physiology and Biophysics, State University of New York at Buffalo, Buffalo, NY, USA.
Aldred S; School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham, UK.

Transl Psychiatry ; 12(1): 285, 2022 07 18.

Article em En | MEDLINE | ID: mdl-35851379

Assuntos

Doença de Alzheimer; Precursor de Proteína beta-Amiloide; Doença de Alzheimer/genética; Secretases da Proteína Precursora do Amiloide/genética; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Citalopram/farmacologia; Citalopram/uso terapêutico; Flavina-Adenina Dinucleotídeo/metabolismo; Flavina-Adenina Dinucleotídeo/farmacologia; Flavina-Adenina Dinucleotídeo/uso terapêutico; Humanos; Neurônios/metabolismo; Estresse Oxidativo; Presenilina-1/genética; Presenilina-1/metabolismo; Inibidores Seletivos de Recaptação de Serotonina/farmacologia; Inibidores Seletivos de Recaptação de Serotonina/uso terapêutico

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Precursor de Proteína beta-Amiloide / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Transl Psychiatry Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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