Sensitive and valid assay for reliable evaluation of drug interactions mediated by human organic anion transporter 1 and 3 using 5-carboxyfluorescein.

Lee, Kyeong-Ryoon; Chang, Ji-Eun; Chae, Yoon-Jee

Lee, Kyeong-Ryoon; Chang, Ji-Eun; Chae, Yoon-Jee.

Afiliação

Lee KR; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.
Chang JE; Department of Bioscience, University of Science and Technology, Daejeon, 34113, Republic of Korea.
Chae YJ; College of Pharmacy, Dongduk Women's University, Seoul, 02748, Republic of Korea.

Anal Sci ; 38(10): 1347-1357, 2022 Oct.

Article em En | MEDLINE | ID: mdl-35882772

Assuntos

Proteína 1 Transportadora de Ânions Orgânicos; Transportadores de Ânions Orgânicos Sódio-Independentes; Interações Medicamentosas; Fluoresceínas; Humanos

Palavras-chave

5-carboxyfluorescein (5-CF); Drug interactions; High-performance liquid chromatography (HPLC); Method validation; Organic anion transporters (OATs)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transportadores de Ânions Orgânicos Sódio-Independentes / Proteína 1 Transportadora de Ânions Orgânicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Anal Sci Ano de publicação: 2022 Tipo de documento: Article

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