Shim coils tailored for correcting B0 inhomogeneity in the human brain (SCOTCH): Design methodology and 48-channel prototype assessment in 7-Tesla MRI.

ABSTRACT

Increased static field inhomogeneities are a burden for human brain MRI at Ultra-High-Field. In particular they cause enhanced Echo-Planar image distortions and signal losses due to magnetic susceptibility gradients at air-tissue interfaces in the subject's head. In the past decade, Multi-Coil Arrays (MCA) have been proposed to shim the field in the brain better than the 2nd or 3rd order Spherical Harmonic (SH) coils usually offered by MRI manufacturers. Here we present a novel MCA, named SCOTCH, optimized for whole brain shimming. Based on a cylindrical structure, it features several layers of small coils whose shape, size and location are found from a principal component analysis of ideal stream functions computed from an internal 100-brain fieldmap database. From an Open-Access external database of 126 brains, our SCOTCH implementation is shown to be equivalent to a partial 7th-order SH system with unlimited power, outperforming all known existing MCA prototypes. This result is further confirmed by a low-cost  30-cm diameter SCOTCH prototype built with 48 coils on 3 layers, and tested on 7 volunteers at 7T with a parallel-transmit RF coil made to be inserted in SCOTCH. Echo-Planar images of the subject brains before and after SCOTCH shimming show large signal recoveries, especially in the prefrontal cortex.