Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN-Î³-induced murine BV2 microglia cells via NF-&#954;B signal pathway.

Bai, Rui-Xue; Chen, Xin-Zhu; Ren, Jin-Feng; Hu, Lang; Li, Hui; Wang, Hui; He, Cheng

Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN-Î³-induced murine BV2 microglia cells via NF-κB signal pathway.

Bai, Rui-Xue; Chen, Xin-Zhu; Ren, Jin-Feng; Hu, Lang; Li, Hui; Wang, Hui; He, Cheng.

Afiliação

Bai RX; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Chen XZ; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Ren JF; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Hu L; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Li H; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Wang H; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China. Electronic address: hui.wang@xzhmu.edu.cn.
He C; Department of Pathogen Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China. Electronic address: hecheng@xzhmu.edu.cn.

Acta Trop ; 235: 106650, 2022 Nov.

Article em En | MEDLINE | ID: mdl-35963313

Assuntos

Microglia; Toxoplasma; Animais; Biomarcadores; Lipopolissacarídeos/metabolismo; Lipopolissacarídeos/farmacologia; Camundongos; Microglia/metabolismo; NF-kappa B/metabolismo; Transdução de Sinais

Palavras-chave

M1 polarization; Microglia; NF-κB signal pathway; TgROP18; Toxoplasma gondii

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma / Microglia Limite: Animals Idioma: En Revista: Acta Trop Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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