KDM1A inhibition increases UVA toxicity and enhances photodynamic therapy efficacy.

Mudambi, Shaila; Fitzgerald, Megan; Pera, Paula; Washington, Deschana; Chamberlain, Sarah; Fidrus, Eszter; Hegedus, Csaba; Remenyik, Eva; Shafirstein, Gal; Bellnier, David; Paragh, Gyorgy

Mudambi, Shaila; Fitzgerald, Megan; Pera, Paula; Washington, Deschana; Chamberlain, Sarah; Fidrus, Eszter; Hegedus, Csaba; Remenyik, Eva; Shafirstein, Gal; Bellnier, David; Paragh, Gyorgy.

Afiliação

Mudambi S; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Fitzgerald M; Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Pera P; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Washington D; Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Chamberlain S; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Fidrus E; Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Hegedus C; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Remenyik E; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Shafirstein G; Photodynamic Therapy Center, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Bellnier D; Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Paragh G; Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Photodermatol Photoimmunol Photomed ; 39(3): 226-234, 2023 May.

Article em En | MEDLINE | ID: mdl-35968606

Assuntos

Histona Desmetilases; Fotoquimioterapia; Pele; Humanos; Ácido Aminolevulínico/farmacologia; Histona Desmetilases/metabolismo; Histona Desmetilases/farmacologia; Queratinócitos/metabolismo; Lipídeos/farmacologia; Espécies Reativas de Oxigênio/metabolismo; Pele/metabolismo; Raios Ultravioleta/efeitos adversos

Palavras-chave

KDM1A inhibitors; photodynamic therapy; reactive oxygen species; skin; ultraviolet A light

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Pele / Histona Desmetilases Limite: Humans Idioma: En Revista: Photodermatol Photoimmunol Photomed Assunto da revista: ALERGIA E IMUNOLOGIA / DERMATOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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