Epigenomics of rats' liver and its cross-species functional annotation reveals key regulatory genes underlying short term heat-stress response.

Dou, Jinhuan; Luo, Hanpeng; Sammad, Abdul; Lou, Wenqi; Wang, Di; Schenkel, Flavio; Yu, Ying; Fang, Lingzhao; Wang, Yachun

Dou, Jinhuan; Luo, Hanpeng; Sammad, Abdul; Lou, Wenqi; Wang, Di; Schenkel, Flavio; Yu, Ying; Fang, Lingzhao; Wang, Yachun.

Afiliação

Dou J; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Luo H; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Sammad A; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Lou W; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Wang D; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Schenkel F; Centre for Genetic Improvement of Livestock, Department of Animal Biosciences, University of Guelph, N1G 2W1 Guelph, Ontario, Canada.
Yu Y; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin
Fang L; MRC Human Genetics Unit at the Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom. Electronic address: Lingzhao.fang@igmm.ed.ac.uk.
Wang Y; Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA, National Engineering Laboratory of Animal Breeding, Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, College of Animal Science and Technology, China Agricultural University, Beijing 100193, Chin

Genomics ; 114(5): 110449, 2022 09.

Article em En | MEDLINE | ID: mdl-35985612

Assuntos

Epigenômica; Perfilação da Expressão Gênica; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Bovinos; Feminino; Fatores de Transcrição Forkhead/genética; Perfilação da Expressão Gênica/métodos; Genes Reguladores; Resposta ao Choque Térmico/genética; Humanos; Fígado; Mamíferos/genética; Ratos

Palavras-chave

ATAC-seq; DNA methylation; Genetic marker; Multi-omics analysis; RNA-sequencing; Transcription factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Perfilação da Expressão Gênica / Epigenômica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Genomics Assunto da revista: GENETICA Ano de publicação: 2022 Tipo de documento: Article

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