A new era for steroid-resistant nephrotic syndrome in childhood.
Kidney Int
; 102(3): 471-473, 2022 09.
Article
em En
| MEDLINE
| ID: mdl-35988934
ABSTRACT
Among youth with incident nephrotic syndrome, those with steroid-resistant nephrotic syndrome (SRNS) often have an ominous clinical course. Identifying them at or shortly after diagnosis would potentially prevent substantial morbidity and even mortality. For those with a specific monogenic form, targeted therapy might be possible, as is the case presently for CoQ10 insufficiency cases. Further, dissecting specific causes and pathways that lead to SRNS may lead to other targeted, potentially highly effective treatments.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome Nefrótica
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
/
Humans
Idioma:
En
Revista:
Kidney Int
Ano de publicação:
2022
Tipo de documento:
Article