Total-body PET: a new paradigm for molecular imaging.
Br J Radiol
; 95(1140): 20220357, 2022 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-35993615
ABSTRACT
Total body (TB) positron emission tomography (PET) instruments have dramatically changed the paradigm of PET clinical and research studies due to their very high sensitivity and capability to image dynamic radiopharmaceutical distributions in the major organs of the body simultaneously. In this manuscript, we review the design of these systems and discuss general challenges and trade-offs to maximize the performance gains of current TB-PET systems. We then describe new concepts and technology that may impact future TB-PET systems. The manuscript summarizes what has been learned from the initial sites with TB-PET and explores potential research and clinical applications of TB-PET. The current generation of TB-PET systems range in axial field-of-view (AFOV) from 1 to 2 m and serve to illustrate the benefits and opportunities of a longer AFOV for various applications in PET. In only a few years of use these new TB-PET systems have shown that they will play an important role in expanding the field of molecular imaging and benefiting clinical practice.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tomografia Computadorizada por Raios X
/
Tomografia por Emissão de Pósitrons
Limite:
Humans
Idioma:
En
Revista:
Br J Radiol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos