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Potential of a glucagon-like peptide-1 receptor/glucose-dependent insulinotropic polypeptide receptor/glucagon receptor triagonist for the treatment of obesity and type 2 diabetes.
Araki, Eiichi; Sakaguchi, Masaji; Fukuda, Kazuki; Kondo, Tatsuya.
Afiliação
  • Araki E; Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Sakaguchi M; Center for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Fukuda K; Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Kondo T; Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
J Diabetes Investig ; 13(12): 1958-1960, 2022 Dec.
Article em En | MEDLINE | ID: mdl-36039895
ABSTRACT
Triagonists of GLP-1R/ GIPR /GCGR, including SAR441255, bind to each receptor and induce specific effects through each receptor signaling pathway, thus result in weight loss and glycemic control in obese T2D animal models.
Assuntos
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 Limite: Animals Idioma: En Revista: J Diabetes Investig Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 Limite: Animals Idioma: En Revista: J Diabetes Investig Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão