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Comparison of Coronally Advanced Flap and Connective Tissue Graft With or Without Enamel Matrix Derivative for Gingival Recession Treatment: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Int J Periodontics Restorative Dent ; 42(5): e121-e131, 2022.
Article em En | MEDLINE | ID: mdl-36044689
The aim of this systematic review and meta-analysis was to assess whether the addition of enamel matrix derivative (EMD) to a coronally advanced flap (CAF) combined with a connective tissue graft (CTG) resulted in a greater amount of root coverage in patients treated for gingival recessions, as compared to CAF+CTG alone. The search for clinical trials on root coverage procedures comparing CAF+CTG+EDM vs CAF+CTG was completed on online databases and gray literature, and it included studies published up to January 2022. The risk of bias was assessed using the Cochrane bias assessment tool, and the quantitative analysis was performed using a random effects model. A total of 1,917 articles were identified, and 12 underwent full-text review. Three studies were excluded, and 9 were selected for full analysis. The meta-analysis showed that there is a statistically significant difference (P = .04) in favor of CAF+CTG+EMD compared to CAF+CTG alone for the amount of root coverage (mean difference: 0.30 mm; 95% CI: 0.01, 0.58 mm). According to the results of this systematic review and meta-analysis, the addition of EMD to CAF+CTG results in a greater amount of root coverage in teeth treated for gingival recessions.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas do Esmalte Dentário / Retração Gengival Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Humans Idioma: En Revista: Int J Periodontics Restorative Dent Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas do Esmalte Dentário / Retração Gengival Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Humans Idioma: En Revista: Int J Periodontics Restorative Dent Ano de publicação: 2022 Tipo de documento: Article